Selectively Inhibiting Ras-p21 by a Synthetic SOS Plasmid: Utilization of a Synthetic SOS Plasmid to Selectively Inhibit Oncogenic Ras-p21 Induced Oocyte Maturation

Selectively Inhibiting Ras-p21 by a Synthetic SOS Plasmid: Utilization of a Synthetic SOS Plasmid to Selectively Inhibit Oncogenic Ras-p21 Induced Oocyte Maturation PDF

Scientific work over the past 30 years revealed that SOS protein is directly involved in the activation of ras-p21.The aim of this research project was to synthesize a plasmid which would ultimately express a SOS peptide, 994-1004, which was proven to inhibitthe Val 12 ras-p21 pathway in Xenopus laevis oocytes. The SOS plasmid consisted of a vector, pOPRSVI/MCS, ligated to DNA oligonucleotides cor...

By Ethia Vitalis
ASIN: 3639059220
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